Endocrine Abstracts

Grave’s disease (GD), like all autoimmune diseases, is predominantly female, with sex ratio to 3 women for one man. The treatment of first intension is based on antithyroid drugs (ATD). Our objective is to compare the clinical presentation and the evolution of GD by gender. It’s a retrospective study. We studied patients with a first diagnosis of GD, in the department of endocrinology in Farhat Hached hospital in Susah, between Juanuary 2010 and December 2015. The pa...

Introduction: Primary hypothyroidism is a common cause of hyperprolactinemia. TSH measurement is part of the first-line investigation of hyperprolactinemia wich usually disappear after L-thyroxine therapy. the presence of pituitary hyperplasia mimicking a pituitary macroadenoma has been reported by several authors, but coexistence oh primary hypothyroidism and prolactinoma is rarely reported.Case: We report a rare case of hyperprolactinemia revealing the...

Background: Antithyroid drugs (ATD) are indicated as first intension in the treatment of Graves’disease (GD). Only two molecules are marketed in Tunisia: Benzylthiouracil (BTU) and Methimazole (MMI). There is still no clear conclusion about the choice of appropriate drug. Our objective was to compare the MMI treatment with the BTU in terms of efficacy and adverse effects (AEs).Methods: It’s a retrospective study. We studied patients with a firs...

Introduction: Acromegaly is a chronic disorder usually caused by growth hormone (GH)-secreting pituitary adenomas. Transsphenoidal surgery remains a treatment of choice for restoring GH to normal levels. The aim of this study was to illustrate the relationship between some factors and transsphenoidal surgery outcomes.Patients and methods: We retrospectively analysed the outcome of 31 patients with acromegaly after initial endoscopic transsphenoidal surge...